The short answer is yes.
For years the answer was plain "No". Then it became "yes, but in an ugly way" as no browser on Mac OS X is yet capable of performing transparent NTLMv2 authentication instead presenting a "domain login popup".
To not make Mac users' life uglier while we are making Windows crowd life easier we've introduced filtering by User-Agent strings so admins can configure EasySSO to ignore any Mac clients and let them use the regular login screen i.e. "fallback" login.
Since October 2015 the answer is an emphatic "yes!" (as we use Macs ourselves) - with Kerberos support added a domain joined Mac can perform transparent automatic no-password asked login into EasySSO-enabled Atlassian application.